16th International Congress on Antiphospholipid Antibodies Task Force Report on Obstetric Antiphospholipid Syndrome

Author:

de Jesús Guilherme R1ORCID,Benson Ashley E2,Chighizola Cecilia B3,Sciascia Savino4ORCID,Branch David W2ORCID

Affiliation:

1. Department of Obstetrics, Universidade do Estado do Rio de Janeiro, Rio de Janeiro, Brazil

2. Obstetrics and Gynecology, University of Utah Health, Salt Lake City, UT, USA

3. Experimental Laboratory of Immunorheumatological Researches, Allergology, Clinical Immunology & Rheumatology Unit, Istituto Auxologico Italiano IRCCS, Milan, Italy

4. Center of Research of Immunopathology and Rare Diseases, Department of Clinical and Biological Sciences, University of Turin, Turin, Italy

Abstract

Obstetric antiphospholipid syndrome (APS) remains a clinical challenge for practitioners, with several controversial points that have not been answered so far. This Obstetric APS Task Force met on the 16th International Congress on Antiphospholipid Antibodies in Manchester, England, to discuss about treatment, diagnostic and clinical aspects of the disease. This report will address evidence-based medicine related to obstetric APS, including limitations on our current management, the relationship between antibodies against domain 1 of β2GPI and obstetric morbidity, hydroxychloroquine use in patients with obstetric APS and factors associated with thrombosis after obstetric APS. Finally, future directions for better understanding this complex condition are also reported by the Task Force coordinators.

Publisher

SAGE Publications

Subject

Rheumatology

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