Current treatment of lupus nephritis-Reference-Cited by-同舟云学术

Current treatment of lupus nephritis

Published:2008-05 Issue:5 Volume:17 Page:426-430
ISSN:0961-2033
Container-title:Lupus
language:en
Short-container-title:Lupus

Author:

Houssiau FA¹,Ginzler EM²

Affiliation:

1. Rheumatology Department, Cliniques Universitaires Saint-Luc, Université catholique de Louvain, Bruxelles, Belgium

2. Division of Rheumatology, State University of New York Downstate Medical Center, Brooklyn, New York, USA

Abstract

This review on the management of lupus nephritis is based on the results of randomized clinical trials, and discusses the principles of treatment and the current options for induction and maintenance therapy. The respective place of mycophenolate mofetil and intravenous cyclophosphamide are balanced, taking into account efficacy, safety and patients’ perspective. The authors anticipate that, in a few years, when long-term data on lupus nephritis patients induced with mycophenolate mofetil becomes available, it is probably that intravenous cyclophosphamide, which has been for so long the ‘standard of care’, will be prescribed only in specialized conditions such as documented necrotizing vasculitis.

Publisher

SAGE Publications

Subject

Rheumatology

Link

http://journals.sagepub.com/doi/pdf/10.1177/0961203308090029

Reference26 articles.

1. Management of Lupus Nephritis: An Update

2. Early response to immunosuppressive therapy predicts good renal outcome in lupus nephritis: Lessons from long-term followup of patients in the Euro-Lupus Nephritis Trial

3. Morbidity and Mortality in Systemic Lupus Erythematosus During a 10-Year Period

4. Mycophenolate Mofetil or Intravenous Cyclophosphamide for Lupus Nephritis

5. Withdrawal of therapy in patients with proliferative lupus nephritis: long-term follow-up

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