Affiliation:
1. Cosmetic Ingredient Review Senior Scientific Analyst/Writer
2. Expert Panel for Cosmetic Ingredient Safety Member
3. Cosmetic Ingredient Review Senior Director
4. Cosmetic Ingredient Review Executive Director
Abstract
The Expert Panel for Cosmetic Ingredient Safety (Panel) first published a safety assessment of Sodium Dehydroacetate and Dehydroacetic Acid in 1985. The Panel previously concluded that Sodium Dehydroacetate and Dehydroacetic Acid are safe as used in the present practices of use and concentration, as stated in that report. Upon re-review in 2003, the Panel reaffirmed the original conclusion, as published in 2006. The Panel reviewed updated frequency and concentration of use data again in 2023, in addition to any newly available, relevant safety data. Considering this information, as well as the information provided in the original safety assessment and the prior re-review document, the Panel reaffirmed the 1985 conclusion.
Funder
Personal Care Products Council
Reference17 articles.
1. 4 Final Report on the Safety Assessment of Sodium Dehydroacetate and Dehydroacetic Acid
2. US Food and Drug Administration (FDA) Center for Food Safety & Applied Nutrition (CFSAN). 2023. Voluntary Cosmetic Registration Program - Frequency of Use of Cosmetic Ingredients. (Obtained under the Freedom of Information Act from CFSAN; requested as “Frequency of Use Data” January 4, 2023; received February 2, 2023). College Park, MD.
3. Personal Care Products Council. Concentration of use by FDA product category: Sodium Dehydroacetate and Dehydroacetic Acid. (Unpublished data submitted by Personal Care Products Council on February 23, 2023). 2023.
4. A repeated dose 28-day oral toxicity study of sodium dehydroacetate (DHA-S) in Wistar rats