Laparoscopic-Guided Ropivacaine Trocar-Site Infiltration Can Improve Post-Operative Pain Control after Laparoscopic Adrenalectomy

Author:

Cavallaro Giuseppe1ORCID,Polistena Andrea1ORCID,Petramala Luigi2,Gazzanelli Sergio1,Crocetti Daniele1,Iorio Olga3,Iossa Angelo4,Fiori Enrico1,Bracale Umberto5ORCID,De Toma Giorgio1,Letizia Claudio2

Affiliation:

1. Department of Surgery “P. Valdoni”, Sapienza University, Rome, Italy

2. Department of Translational and Precision Medicine, Sapienza University, Rome, Italy

3. General Surgery Unit, F. Spaziani Hospital, Frosinone, Italy

4. Department of Medico-Surgical Sciences and Biotechnologies, Sapienza University, Rome, Italy

5. Department of Advanced Biomedical Sciences, Federico II University, Naples, Italy

Abstract

Background There is no consensus on pain control in patients undergoing laparoscopy; nowadays, conventional therapy may be improved by transversus abdominis plane block. The aim of this evaluation is to investigate the role of laparoscopic-assisted trocar-site ropivacaine infiltration during adrenalectomy in pain control Methods This is a retrospective evaluation of a prospectively maintained database including patients undergoing adrenalectomy. Patients were divided into 2 groups: Group A patients received laparoscopic-assisted trocar-site infiltration of 7.5 mg/mL ropivacaine and Group B patients did not receive any infiltration. All patients received a 24-hour infusion of 20 mg morphine; pain was checked at 6, 24, and 48 hours after surgery by Visual Analogue Scale (VAS) score. A rescue analgesia by was given if VAS score was > 4 or on patient request. Results No differences in operative time, complications, and post-operative stay and no complications related to trocar-site infiltration were found. 6-hour and 48-hour VAS scores were not found to be significantly different between groups, even if a slight decrease in VAS score in Group A was reported. Group A showed significant reduction in VAS score at 24 hours (2.44 +/− .41 vs 3.01 +/− .78, P < .005) and in the number of patients requiring further analgesic drugs administration (40.6% vs 57.8%, P < .005) Conclusions Laparoscopic-guided trocar-site ropivacaine infiltration can be considered safe and effective in the management of post-operative pain and in the reduction of analgesic need in patients undergoing laparoscopic adrenalectomy. The retrospective nature of the study and the lack of a consistent series of patients require further evaluations.

Publisher

SAGE Publications

Subject

Surgery

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