Is Colchicine the New “Aspirin”?

Abstract

For more than six decades, ischemic heart disease has sustained as the world’s leading cause of death. Growing evidence suggests chronic inflammation as the underlying pathophysiology of this illness. Due to this, inflammatory markers have become a mainstay of diagnosing, prognosticating, and following up the effectiveness of therapy. Colchicine remains a contentious treatment option for coronary heart disease, despite mounting evidence to the contrary from recent studies. This article discusses the basics of inflammation, the role of colchicine, various clinical studies, and the latest guidelines on colchicine. Colchicine has the potential to develop into a cheap, novel, and effective therapy for coronary artery disease.