Chemical and Genetic Identity of Ligularia tsangchanensis and L. muliensis. Isolation of a Cacalol Precursor from a Hybrid of L. tsangchanensis and L. vellerea-Reference-Cited by-同舟云学术

Chemical and Genetic Identity of Ligularia tsangchanensis and L. muliensis. Isolation of a Cacalol Precursor from a Hybrid of L. tsangchanensis and L. vellerea

Published:2018-04 Issue:4 Volume:13 Page:1934578X1801300
ISSN:1934-578X
Container-title:Natural Product Communications
language:en
Short-container-title:Natural Product Communications

Author:

Kuroda Chiaki¹,Itoh Taketo¹,Suzuki Yurika¹,Suzuki Yuko¹,Okamoto Yasuko²,Tori Motoo²,Hanai Ryo³,Gong Xun⁴

Affiliation:

1. Department of Chemistry, Rikkyo University, Nishi-Ikebukuro, Toshima-ku, Tokyo 171-8501, Japan

2. Faculty of Pharmaceutical Sciences, Tokushima Bunri University, Yamashiro-cho, Tokushima 770–8514, Japan

3. Department of Life Science, Rikkyo University, Nishi-Ikebukuro, Toshima-ku, Tokyo 171–8501, Japan

4. Kunming Institute of Botany, Chinese Academy of Science, Kunming 650201, China

Abstract

The chemical composition and the DNA sequence of an evolutionarily neutral region were studied for three samples of L. tsangchanensis, three samples of L. muliensis, and one sample of a hybrid between L. tsangchanensis and L. vellerea. L. tsangchanensis and L. muliensis were indistinguishable in the chemical composition and the ITS sequence, supporting a recent taxonomic study that merged the two species into L. tsangchanensis. Cacalol (1) was isolated as the most major component from both L. tsangchanensis and L. muliensis, while 6-acetoxy-9-oxofuranoeremophilane (10), a putative cacalol precursor, was isolated from the hybrid.

Publisher

SAGE Publications

Subject

Complementary and alternative medicine,Plant Science,Drug Discovery,Pharmacology,General Medicine

Link

http://journals.sagepub.com/doi/pdf/10.1177/1934578X1801300402

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