Affiliation:
1. Key Laboratory of Basic and Application Research of Beiyao (Heilongjiang University of Chinese Medicine), Ministry of Education, Harbin, P.R. China
2. Shanxi University of Traditional Chinese Medicine, Jinzhong, P.R. China
Abstract
In the course of chemical investigations of Datura metel L., a new sesquiterpenoid, dmetelin J (1) was isolated from the leaves, along with the 4 known compounds apocynol A (2), blumenol B (3), megastigmane (4), and ( + )-dehydrovomifoliol (5). Structure elucidation was performed by spectroscopic techniques, including 1- and 2-dimensional NMR spectroscopy and HRESIMS. Compounds 2, 3, and 5 were isolated from the Solanaceae for the first time. All isolated compounds were subjected to anti-inflammatory activity evaluation.
Funder
National Natural Science Foundation of China
Heilongjiang Touyan Innovation Team Program
Excellent Youth Project of Heilongjiang Natural Science Foundation
Subject
Complementary and alternative medicine,Plant Science,Drug Discovery,Pharmacology,General Medicine
Reference23 articles.
1. National Pharmacopoeia Commission. Pharmacopoeia of the People’s Republic of China. Part I. 2015;Part 1:267.
2. New antiproliferative and immunosuppressive withanolides from the seeds of Datura metel