Male factor infertility: A contemporary overview of investigation, diagnosis and management-Reference-Cited by-同舟云学术

Male factor infertility: A contemporary overview of investigation, diagnosis and management

Published:2022-08-01 Issue: Volume: Page:205141582210784
ISSN:2051-4158
Container-title:Journal of Clinical Urology
language:en
Short-container-title:Journal of Clinical Urology

Author:

Krishan Anil¹^ORCID,Vukina Josip²,Pearce Ian³,Modgil Vaibhav³⁴

Affiliation:

1. University Hospitals Birmingham NHS Foundation Trust, UK

2. University of Pittsburgh School of Medicine, USA

3. Manchester University NHS Foundation Trust, UK

4. Department of Urology, Manchester Royal Infirmary, UK

Abstract

Infertility, defined as the failure to achieve a clinical pregnancy after 1 year of regular, unprotected sexual intercourse, is a public health issue of global concern. It affects up to 12% of couples worldwide. While traditionally, research and treatment have focused on female causes of infertility, male factors contribute to up to 70% of cases and therefore deserve appropriate recognition. The purpose of this comprehensive review is to detail the diagnostic work-up, investigations and management of male factor infertility. We discuss much-debated pathologies, such as varicocele, and novel investigations, including sperm DNA fragmentation and reactive oxygen species.Level of evidence: Not applicable

Publisher

SAGE Publications

Subject

Urology,Surgery

Link

http://journals.sagepub.com/doi/pdf/10.1177/20514158221078474

Reference118 articles.

1. International Committee for Monitoring Assisted Reproductive Technology (ICMART) and the World Health Organization (WHO) revised glossary of ART terminology, 2009∗

2. Fertility and infertility: Definition and epidemiology

3. The Epidemiology of Male Infertility

4. Male factor infertility