Uterine sarcomas: clinical practice guidelines for diagnosis, treatment, and follow-up, by Spanish group for research on sarcomas (GEIS)

Author:

Pérez-Fidalgo Jose Alejandro1,Ortega Eugenia2,Ponce Jordi3,Redondo Andres4,Sevilla Isabel5,Valverde Claudia6,Isern Verdum Josep7ORCID,de Alava Enrique89,Galera López Mar10,Marquina Gloria1112,Sebio Ana131415

Affiliation:

1. Oncology and Hematology Department, INCLIVA Biomedical Research Institute, Hospital Clínico Universitario, CIBERONC Spain, Avda Blasco Ibañez 17, Valencia, 46010, Spain

2. Medical Oncology Department, Hospital Universitario Miguel Servet, Zaragoza, Spain

3. Gynecology Department, Hospital Universitario de Bellvitge. IDIBELL. Universidad de Barcelona, Barcelona, Spain

4. Medical Oncology Department, Hospital Universitario La Paz-IdiPAZ, Madrid, Spain

5. Clinical and Translational Research in Cancer/Instituto de Investigaciones Biomédicas de Málaga (IBIMA)/Hospitales Universitarios Regional and Virgen de la Victoria de Málaga, Málaga, Spain

6. Medical Oncology Department, Vall d’Hebron University Hospital, Barcelona, Spain

7. Radiotherapy Department, Hospital de la Santa Creu i Sant Pau, Universitat Autònoma de Barcelona, Barcelona, Spain

8. Institute of Biomedicine of Sevilla (IBiS), Virgen del Rocio University Hospital /CSIC/University of Sevilla/CIBERONC, Sevilla, Spain

9. Department of Normal and Pathological Cytology and Histology, School of Medicine, University of Seville, Seville, Spain

10. Medical Oncology Department, Hospital General Universitario Gregorio Marañón, Madrid, Spain

11. Department of Medical Oncology, Hospital Clinico San Carlos, Madrid, IdISSC, Spain

12. Department of Medicine, School of Medicine, Complutense University (UCM), Madrid, IdISSC, Spain

13. Medical Oncology Department, Hospital de la Santa Creu i Sant Pau, Barcelona

14. Universitat Autònoma de Barcelona, Barcelona, Spain

15. Institut de Recerca Biomèdica Sant Pau (IIB Sant Pau), Barcelona, Spain

Abstract

Uterine sarcomas are very infrequent and heterogeneous entities. Due to its rarity, pathological diagnosis, surgical management, and systemic treatment are challenging. Treatment decision process in these tumors should be taken in a multidisciplinary tumor board. Available evidence is low and, in many cases, based on case series or clinical trials in which these tumors have been included with other soft tissue sarcoma. In these guidelines, we have tried to summarize the most relevant evidence in the diagnosis, staging, pathological disparities, surgical management, systemic treatment, and follow-up of uterine sarcomas.

Publisher

SAGE Publications

Subject

Oncology

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