Epidemiology of Gastric Intestinal Metaplasia and Gastric Cancer-Reference-Cited by-全球学者库

Epidemiology of Gastric Intestinal Metaplasia and Gastric Cancer

Published:2023-02-06 Issue:1 Volume:3 Page:80-88
ISSN:2634-5161
Container-title:Foregut: The Journal of the American Foregut Society
language:en
Short-container-title:Foregut: The Journal of the American Foregut Society

Author:

Pham Codey¹,Nguyen Wenker Theresa¹²^ORCID,El-Serag Hashem B¹²

Affiliation:

1. Department of Medicine, Baylor College of Medicine, Houston, TX, USA

2. Center for Innovations in Quality, Effectiveness and Safety (IQuESt), Michael E DeBakey Veterans Affairs Medical Center, Houston, TX, USA

Abstract

Gastric cancer remains one of the most common cancers globally. The pathogenesis of intestinal-type gastric cancer involves pre-malignant stages, including gastric intestinal metaplasia (GIM), the replacement of native gastric foveolar and/or glandular epithelium by intestinal-type epithelium. GIM prevalence is highly variable based on geography and race/ethnicity partly due to the varying prevalence of H. pylori, a potent risk factor. However, gastric cancer incidence does not mirror that of H. pylori, demonstrating a complex interaction between H. pylori and risk factors. We will discuss the epidemiology of GIM and gastric cancer, including incidence trends, risk factors, and implications for future management.

Funder

National Institute of Diabetes and Digestive and Kidney Diseases

National Institutes of Health

Texas Digestive Disease Center

Publisher

SAGE Publications

Link

http://journals.sagepub.com/doi/pdf/10.1177/26345161231154024

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