The microcirculation and its measurement in sepsis-Reference-Cited by-同舟云学术

The microcirculation and its measurement in sepsis

Published:2016-11-10 Issue:3 Volume:18 Page:221-227
ISSN:1751-1437
Container-title:Journal of the Intensive Care Society
language:en
Short-container-title:Journal of the Intensive Care Society

Author:

Charlton Matthew¹,Sims Mark²,Coats Tim³,Thompson Jonathan P¹

Affiliation:

1. Anaesthetics and Critical Care, Diagnostic Development Unit, University of Leicester, Leicester, UK

2. Astrobiology and Space Instrumentation, Diagnostic Development Unit, University of Leicester, Leicester, UK

3. Emergency Medicine, Diagnostic Development Unit, University of Leicester, Leicester, UK

Abstract

The microcirculation describes the smallest elements of the cardiovascular conducting system and is pivotal in the maintenance of homeostasis. Microcirculatory dysfunction is present early in the pathophysiology of sepsis, with the extent of microcirculatory derangement relating to disease severity and prognosis in ICU patients. However, at present microcirculatory function is not routinely monitored at the bedside. This article describes the pathophysiology of microcirculatory derangements in sepsis, methods of its measurement and evidence to support their clinical use.

Publisher

SAGE Publications

Subject

Critical Care and Intensive Care Medicine,Critical Care Nursing

Link

http://journals.sagepub.com/doi/pdf/10.1177/1751143716678638

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