1. Department of Gastroenterology, Vila Nova de Gaia Espinho Hospital Center, Vila Nova de Gaia, Portugal
2. Department of Biomedicine, Unit of Pharmacology and Therapeutics, Faculty of Medicine, University of Porto, Porto, Portugal
3. Unidade de Farmacologia Clínica, São João Hospital University Centre, Porto, Portugal
4. Portuguese Group of Studies in Inflammatory Bowel Disease (Grupo de Estudos da Doença Inflamatória Intestinal - GEDII), Porto, Portugal
5. Center for Health Technology and Services Research (CINTESIS), Porto, Portugal
6. Department of Biomedicine, Unit of Pharmacology and Therapeutics, Faculty of Medicine, University of Porto, Rua Dr. Plácido Costa, 3, Porto 4200-450, Portugal
7. Department of Gastroenterology, São João Hospital University Centre, Porto, Portugal