Gastric cancer and trastuzumab: first biologic therapy in gastric cancer

Author:

Gunturu Krishna S.1,Woo Yanghee2,Beaubier Nike2,Remotti Helen E.2,Saif M. Wasif3

Affiliation:

1. Division of Hematology/Oncology, Tufts Medical Center, Boston, MA, USA

2. Columbia University College of Physicians and Surgeons and the Herbert Irving Cancer Center, New York, NY, USA

3. Department of Medicine and Cancer Center, Tufts Medical Center, 800 Washington Street Box 245, Boston, MA 02111, USA

Abstract

Gastric cancer remains difficult to cure and has a poor overall prognosis. Chemotherapy and multimodality therapy has shown some benefit in the treatment of gastric cancer. Current therapies for gastric cancer have their limitations; thus, we are in need of newer treatment options including targeted therapies. Here, we review the biologic therapy with trastuzumab in human epidermal growth factor receptor 2 (HER2)+ gastric cancer.

Publisher

SAGE Publications

Subject

Oncology

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