Challenges of Glycemic Control in People With Diabetes and Advanced Kidney Disease and the Potential of Automated Insulin Delivery-Reference-Cited by-同舟云学术

Challenges of Glycemic Control in People With Diabetes and Advanced Kidney Disease and the Potential of Automated Insulin Delivery

Published:2023-05-10 Issue: Volume: Page:193229682311740
ISSN:1932-2968
Container-title:Journal of Diabetes Science and Technology
language:en
Short-container-title:J Diabetes Sci Technol

Author:

Lu Jean C.¹²³^ORCID,Lee Petrova⁴,Ierino Francesco¹⁴⁵,MacIsaac Richard J.¹²³,Ekinci Elif³⁶⁷,O’Neal David¹²³^ORCID

Affiliation:

1. Department of Medicine, St Vincent’s Hospital Melbourne, The University of Melbourne, Fitzroy, VIC, Australia

2. Department of Endocrinology and Diabetes, St Vincent’s Hospital Melbourne, Fitzroy, VIC, Australia

3. Australian Centre for Accelerating Diabetes Innovations, The University of Melbourne, Parkville, VIC, Australia

4. Department of Nephrology, St Vincent’s Hospital Melbourne, Fitzroy, VIC, Australia

5. St Vincent’s Institute of Medical Research, Fitzroy, VIC, Australia

6. Department of Endocrinology and Diabetes, Austin Health, Heidelberg, VIC, Australia

7. Department of Medicine, Austin Hospital, The University of Melbourne, Heidelberg, VIC, Australia

Abstract

Diabetes is the leading cause of chronic kidney disease (CKD) and end-stage kidney disease in the world. It is known that maintaining optimal glycemic control can slow the progression of CKD. However, the failing kidney impacts glucose and insulin metabolism and contributes to increased glucose variability. Conventional methods of insulin delivery are not well equipped to adapt to this increased glycemic lability. Automated insulin delivery (AID) has been established as an effective treatment in patients with type 1 diabetes mellitus, and there is emerging evidence for their use in type 2 diabetes mellitus. However, few studies have examined their role in diabetes with concurrent advanced CKD. We discuss the potential benefits and challenges of AID use in patients with diabetes and advanced CKD, including those on dialysis.

Publisher

SAGE Publications

Subject

Biomedical Engineering,Bioengineering,Endocrinology, Diabetes and Metabolism,Internal Medicine

Link

http://journals.sagepub.com/doi/pdf/10.1177/19322968231174040

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