Curcumin-Impregnated Drug Delivery Systems May Show Promise in the Treatment of Diseases Secondary to Traumatic Brain Injury: Systematic Review-Reference-Cited by-同舟云学术

Curcumin-Impregnated Drug Delivery Systems May Show Promise in the Treatment of Diseases Secondary to Traumatic Brain Injury: Systematic Review

Published:2022-06 Issue:2 Volume:13 Page:190-196
ISSN:0976-500X
Container-title:Journal of Pharmacology and Pharmacotherapeutics
language:en
Short-container-title:Journal of Pharmacology and Pharmacotherapeutics

Author:

Yilmaz İbrahim¹²^ORCID,Karaarslan Numan³^ORCID,Somay Hakan⁴^ORCID,Ozbek Hanefi⁵^ORCID,Ates Ozkan⁶^ORCID

Affiliation:

1. Ministry of Health, Dr Ismail Fehmi Cumalioglu City Hospital, Unit of Pharmacovigilance and Rational Use of Drugs, Tekirdag, Turkey

2. Department of Medical Services and Techniques, Vocational School of Health Services, Istanbul Rumeli University, Istanbul, Istanbul, Turkey

3. Department of Neurosurgery, Halic University School of Medicine, Istanbul, Istanbul, Turkey

4. Department of Neurosurgery, Kadikoy Medicana Hospital, Istanbul, Istanbul, Turkey

5. Department of Medical Pharmacology, İzmir Bakırçay University School of Medicine, Izmir, Izmir, Turkey

6. Department of Neurosurgery, Istanbul Koc University School of Medicine, Istanbul, Istanbul, Turkey

Abstract

Objective To find out whether curcumin can be effective in the treatment of traumatic brain injury (TBI). Methods A comprehensive and systematic literature search in the PubMed electronic database was performed. Descriptive statistics were used to evaluate the data obtained. The results were presented as frequency and percentage (%) or amount. Results Two clinical trials investigated curcumin for the treatment of TBI. One study tested curcumin in living mammalian subjects using an amyloLipid nanovesicle. In three studies, curcumin was investigated together with the drug delivery system for the treatment of TBI. Conclusion Drug delivery systems prepared with nanomaterials may have a potential therapeutic effect in treating TBI by increasing neuroprotection because they can penetrate the central nervous system more rapidly.

Publisher

SAGE Publications

Subject

Pharmacology (medical),Pharmacology

Link

http://journals.sagepub.com/doi/pdf/10.1177/0976500X221112479

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