The evaluation, diagnosis, and treatment of malignant mixed Müllerian tumor of the cervix: A case report

Abstract

Introduction: Cervical cancer is the most common gynecologic malignancy in India, the most common histology being squamous cell carcinoma. Malignant mixed Müllerian tumor of the cervix, also referred to as carcinosarcoma of the cervix is an unusual entity. Hence, there is a dearth of literature on evaluation and management of such tumors, which is also reflected in the fact that there are no specific consensus guidelines on the same. We present the case of a 35-year-old woman who was diagnosed to have malignant mixed Müllerian tumor of the cervix. Case Report: Carcinosarcoma cervix is a rare entity, with postmenopausal women being more commonly affected. This makes our case a very unique one, as our patient is a premenopausal, 35-year-old young woman who presented with abnormal uterine bleeding and was subsequently diagnosed to have carcinosarcoma of the cervix. The clinical presentation and management of the case have been discussed. Conclusion: Malignant mixed Müllerian tumor is an aggressive and rare tumor which can affect the uterus, ovaries, or the cervix. A negative biopsy may not help to rule out the diagnosis of the same. Multimodality treatment including surgical intervention, chemotherapy with paclitaxel and carboplatin, and radiotherapy could benefit this subset of patients.