Strategies for delivering porphyrinoid-based photosensitizers in therapeutic applications-Reference-Cited by-同舟云学术

Strategies for delivering porphyrinoid-based photosensitizers in therapeutic applications

Published:2014-07 Issue:7 Volume:5 Page:859-872
ISSN:2041-5990
Container-title:Therapeutic Delivery
language:en
Short-container-title:Therapeutic Delivery

Author:

Samaroo Diana¹,Perez Evelyn¹,Aggarwal Amit²,Wills Andrew¹,O'Connor Naphtali³

Affiliation:

1. Department of Chemistry, New York City College of Technology, 300 Jay Street, Brooklyn, NY 11201, USA

2. Department of Science, Borough of Manhattan Community College, 199 Chambers Street, New York, NY 10007, USA

3. Department of Chemistry, Lehman College, 250 Bedford Park Blvd W, New York, NY 10468, USA

Abstract

Delivery strategies for porphyrinoid-based photosensitizers for use in therapeutic applications are based on a myriad of factors, which include porphyrinoid structure, solubility and cellular targets. These drug-delivery methods include encapsulation, hydrogels, protein carriers, nanoparticles and polymeric micelles among others. This article reviews the strategies for delivering porphyrinoids published to date and will focus on porphyrins, corroles, chlorins, bacteriochlorins, porphyrazines and phthalocyanines. Highlighted are the most recent and different strategies used for each of the corresponding porphyrinoid-based macrocycles.

Publisher

Future Science Ltd

Subject

Pharmaceutical Science

Link

http://www.future-science.com/doi/pdf/10.4155/tde.14.46

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