Structural basis of malaria transmission blockade by a monoclonal antibody to gamete fusogen HAP2
Author:
Affiliation:
1. Program in Cellular and Molecular Medicine, Boston Children's Hospital
2. School of Life Sciences, Nanjing University
3. Burnet Institute
4. Department of Pathology, University of Cambridge
5. Boston Children's Hospital
Abstract
Funder
National Institutes of Health
Boston Children's Hospital
Medical Research Council
Isaac Newton Trust
Alborada Trust
Wellcome Trust
University of Cambridge
Global Health Innovative Technology Fund
Rosetrees Trust
Royal Society
Publisher
eLife Sciences Publications, Ltd
Subject
General Immunology and Microbiology,General Biochemistry, Genetics and Molecular Biology,General Medicine,General Neuroscience
Link
https://cdn.elifesciences.org/articles/74707/elife-74707-v3.pdf
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2. Targeting the Conserved Fusion Loop of HAP2 Inhibits the Transmission of Plasmodium berghei and falciparum;Angrisano;Cell Reports,2017
3. Structural basis of differential neutralization of DENV-1 genotypes by an antibody that recognizes a cryptic epitope;Austin;PLOS Pathogens,2012
4. Protein O- and C-Glycosylation pathways in Toxoplasma gondii and Plasmodium falciparum;Bandini;Parasitology,2019
5. Species-Specific Functional Regions of the Green Alga Gamete Fusion Protein HAP2 Revealed by Structural Studies;Baquero;Structure,2019
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