Kinesin-4 KIF21B limits microtubule growth to allow rapid centrosome polarization in T cells
Author:
Affiliation:
1. Cell Biology, Neurobiology and Biophysics, Department of Biology, Faculty of Science, Utrecht University, Utrecht, Netherlands
2. Center for Translational Immunology, University Medical Center Utrecht, Utrecht University, Utrecht, Netherlands
Abstract
Funder
European Research Council
Nederlandse Organisatie voor Wetenschappelijk Onderzoek
Publisher
eLife Sciences Publications, Ltd
Subject
General Immunology and Microbiology,General Biochemistry, Genetics and Molecular Biology,General Medicine,General Neuroscience
Link
https://cdn.elifesciences.org/articles/62876/elife-62876-v2.pdf
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3. INF2 promotes the formation of detyrosinated microtubules necessary for centrosome reorientation in T cells;Andrés-Delgado;Journal of Cell Biology,2012
4. Mutations in the KIF21B kinesin gene cause neurodevelopmental disorders through imbalanced canonical motor activity;Asselin;Nature Communications,2020
5. Genome-wide association defines more than 30 distinct susceptibility loci for crohn's disease;Barrett;Nature Genetics,2008
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