Formulation and Evaluation of Immediate Release Tablets of Zopiclone-Reference-Cited by-同舟云学术

Formulation and Evaluation of Immediate Release Tablets of Zopiclone

Published:2023-08-31 Issue: Volume: Page:3755-3758
ISSN:0974-360X
Container-title:Research Journal of Pharmacy and Technology
language:en
Short-container-title:RJPT

Author:

Devi Gottemukkula Lakshmi¹,Singh Rishika¹,Prathyusha N.¹,Akhila J.¹,Devender B.¹,Sri. S Ramya²

Affiliation:

1. Department of Pharmaceutics, Joginpally B. R Pharmacy College, Moinabad, Hyderabad, Telangana, India.

2. Department of Pharmaceutics, University College of Technology, Osmania University, Hyderabad, Telangana, India.

Abstract

The current study's objective is to directly compress a Zopiclone rapid release tablet and assess it. The superdisintegrants (crospovidone, croscarmellose sodium, fenugreek) were used to hasten drug release from tablets. The prepared tablets pre-compression, post-compression characteristics were scrutinised. The interactions between the medication excipients were investigated using FTIR. The research shows that direct compression F3 formulations had a faster drug release of 100.05% over a 45-minute period than other Zopiclone formulations, which had lower dissolving rates when utilising Crospovidone.

Publisher

A and V Publications

Subject

Pharmacology (medical),Pharmacology, Toxicology and Pharmaceutics (miscellaneous)

Reference11 articles.

1. Manish J, Sonam R, Amit K, Sanjay KS, Bhupendra SC. A Review On Immediate Release Drug Delivery System By Using Design Of Experiment. Journal of Drug Discovery and Therapeutics. 2013; 1 (12): 21-7.

2. Vaseeha Banu TS, Jaiswal VA, Mohammad SA. Formulation and Evaluation of Transdermal Patches of Decongestant Drug. Research Journal of Pharmaceutical Dosage Forms and Technology. 2022; 14(3): 195-8.

3. Dedhiya MG, Rastogi SK, Chhettry A. Lercanidipine Immediate Release Compositions. United States Patient Application. 2006; 134-212.

4. Patrik E, Barbro J. New Oral Immediate Release Dosage Form. United States Patient Application. 2006.

5. Kaur V, Mehara N. A Review on: Importance of Superdisintegrant on Immediate Release Tablets. International Journal of Research and Scientific Innovation. 2016; 3: 39-43.