The role of human paillomavirus in the development of squamous urothelial metaplasia

Author:

Galkina Natalya G.,Galkin Alexey V.,Kaganov Oleg I.

Abstract

Squamous metaplasia of the vesical triangle urothelium often accompanies chronic cystitis in women with dysuric simptoms. There is no generally accepted diagnosis and treatment of this condition. The etiological factor is unknown. Thus it is very important to determine the etiological factor in the development of dysuria in women with squamous metaplasia. 50 women with the signs of urothelial squamous metaplasia and persistent or recurrent dysuria for more than 6 months participated in our study. All patients underwent cystoscopy, biopsy was taken from the site suspicious for squamous metaplasia. Urethra scraping was also performed. The samples were tested for the DNA of the human papillomavirus (HPV). HPV was found in 41 patients (82%). Consequently, it can be supposed that the human papillomavirus can be the cause of dysuria in women with squamous metaplasia of the vesical triangle.

Publisher

ECO-Vector LLC

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