Incidence of depressive and anxiety disorders in COVID-19 patients

Abstract

The aim of this study is to analyze the occurrence of depressive and anxiety disorders in patients with COVID-19 and to study the relationship of these disorders with organic damage to the central nervous system. Material and methods. An analysis of occurrence of depressive and anxiety disorders in patients with COVID-19 was carried out at the infectious hospital of the KBGMU for the period June-August 2020. Depression and anxiety were identified using the Hospital Anxiety and Depression Scale (HADS) and compared with the MRI data of the brain. Statistical data processing was carried out using Microsoft Excel 7.0. Results. According to the analysis, out of 76 patients with COVID-19, depressive disorders were observed in 36 (46.3%) patients, anxiety disorders subclinical anxiety in 16 (21.05%), clinical anxiety in 19 (25%). The absence of depressive disorders was observed in 40 (52.63%), the absence of anxiety in 41 (53.94%). By gender differentiation of patients, depressive disorders in men 20 (46.5%), women 16 (48.48%). Anxiety disorders: subclinical anxiety in men 11 (25.5%), women 5 (15.15 %), clinical anxiety in men 7 (16.2%), women 12 (36.36%). The average age of patients at the time of the study was 45.7 years. When conducting MRI of brain, organic lesions were detected in 12 (16%) people, in 64 (84%) at the time of the study, organic lesions were not detected. When collecting a follow-up in 31 patients, depressive disorders were noted in 8 (25.8%), subclinical anxiety 2 (6.45%), clinical anxiety 2 (6.45%), no anxiety 27 (87.09%), no depression 23 (74.19%). No organic lesions were found at the time of MRI of brain. Conclusion. When studying the occurrence of depressive and anxious states and their organic substrates, we found that there is no clear relationship between them and rather have a functional character.