Fungal Otomastoiditis caused by Aspergillus fumigatus in an immunocompromised patient: case report and literature review
-
Published:2024-01-24
Issue:2
Volume:5
Page:448-451
-
ISSN:2675-5459
-
Container-title:South Florida Journal of Development
-
language:
-
Short-container-title:S. F. J. of Dev.
Author:
Rodríguez Juan Carlos Rivas,Zamorano Daniel Contreras,García Estrella Viridiana Enríquez,Soriano Carlos Ricardo Flores,Corona Alfredo Raúl Rodolfo Morayta Ramírez
Abstract
This case report describes a 10-year-old male diagnosed with high-risk B-cell Acute Lymphoblastic Leukemia at a tertiary care center undergoing consolidation with the Total XV protocol. The patient, with a history of Rhino-sinusal Aspergillosis and secondary prophylaxis, presented with recurrent middle ear infections, bilateral non-purulent serous discharge, otalgia, mastoid pain, persistent high-grade fever, and profound neutropenia. Fungal ostomastoiditis was diagnosed and treated with targeted antifungals, yielding a positive response.
Publisher
South Florida Publishing LLC
Reference5 articles.
1. - Arastehfar, A., Carvalho, A., Houbraken, J., Lombardi, L., Garcia-Rubio, R., Jenks, J. D., Rivero-Menendez, O., Aljohani, R., Jacobsen, I. D., Berman, J., Osherov, N., Hedayati, M. T., Ilkit, M., Armstrong-James, D., Gabaldón, T., Meletiadis, J., Kostrzewa, M., Pan, W., Lass-Flörl, C., Perlin, D. S., … Hoenigl, M. (2021). Aspergillus fumigatus and aspergillosis: From basics to clinics. Studies in mycology, 100, 100115. 2. - Kwon-Chung, K. J., & Sugui, J. A. (2013). Aspergillus fumigatus--what makes the species a ubiquitous human fungal pathogen?. PLoS pathogens, 9(12), e1003743. 3. - Ali, K., Hamed, M. A., Hassan, H., Esmail, A., and Sheneef, A. (2018). Identification of fungal pathogens in otomycosis and their drug sensitivity: our experience. Int. Arch. Otorhinolaryngol. 22, 400–403. 4. -Latgé, J. P., & Chamilos, G. (2019). Aspergillus fumigatus and Aspergillosis in 2019. Clinical microbiology reviews, 33(1), e00140-18. 5. -Merad, Y., Derrar, H., Belmokhtar, Z., and Belkacemi, M. (2021). Aspergillus genus and its various human superficial and cutaneous features. Pathogens 10, 643
|
|