Long-acting lenacapavir acts as an effective preexposure prophylaxis in a rectal SHIV challenge macaque model

Author:

Bekerman Elena,Yant Stephen R.,VanderVeen Laurie,Hansen Derek,Lu Bing,Rowe William,Wang Kelly,Callebaut Christian

Funder

Gilead Sciences

Publisher

American Society for Clinical Investigation

Subject

General Medicine

Reference32 articles.

1. CDC. Core Indicators for Monitoring the Ending the HIV Epidemic Initiative (Preliminary Data): National HIV Surveillance System Data Reported through June 2021; and Preexposure Prophylaxis (PrEP) Data Reported through March 2021. https://www.cdc.gov/hiv/library/reports/surveillance-data-tables/ Updated October, 2021 Accessed Dec 12, 2022

2. Characterization of HIV Preexposure Prophylaxis Use Behaviors and HIV Incidence Among US Adults in an Integrated Health Care System

3. Inhibitors of the HIV-1 capsid, a target of opportunity

4. Capsid Inhibition with Lenacapavir in Multidrug-Resistant HIV-1 Infection

5. Two-dose emtricitabine/tenofovir alafenamide plus bictegravir prophylaxis protects macaques against SHIV infection

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