Hypoxia-activated prodrug and antiangiogenic therapies cooperatively treat pancreatic cancer but elicit immunosuppressive G-MDSC infiltration
Author:
Funder
National Cancer Institute
Publisher
American Society for Clinical Investigation
Subject
General Medicine
Link
https://insight.jci.org/articles/view/169150/files/pdf
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1. Safety and Activity of Anti–PD-L1 Antibody in Patients with Advanced Cancer
2. Phase 2 Trial of Single Agent Ipilimumab (Anti-CTLA-4) for Locally Advanced or Metastatic Pancreatic Adenocarcinoma
3. Hypoxia-Targeting Drug Evofosfamide (TH-302) Enhances Sunitinib Activity in Neuroblastoma Xenograft Models
4. Hypoxia Reduction Sensitizes Refractory Cancers to Immunotherapy
5. Pancreatic tumors show high levels of hypoxia
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