Hyperphosphorylation of BCL-2 family proteins underlies functional resistance to venetoclax in lymphoid malignancies

Author:

Chong Stephen Jun Fei,Zhu Fen,Dashevsky Olga,Mizuno Rin,Lai Jolin X.H.,Hackett LiamORCID,Ryan Christine E.ORCID,Collins Mary C.ORCID,Iorgulescu J. BryanORCID,Guièze Romain,Penailillo JohanyORCID,Carrasco Ruben,Hwang Yeonjoo C.ORCID,Muñoz Denise P.ORCID,Bouhaddou Mehdi,Lim Yaw Chyn,Wu Catherine J.,Allan John N.,Furman Richard R.ORCID,Goh Boon Cher,Pervaiz Shazib,Coppé Jean-PhilippeORCID,Mitsiades Constantine S.ORCID,Davids Matthew S.ORCID

Funder

Simeon J. Fortin Charitable Foundation

Leukemia and Lymphoma Society

National Institutes of Health

Dana-Farber Cancer Institute Lymphoma Pilot Grant

Dana-Farber Cancer Institute Medical Oncology Grant Program

Novartis Drug Discovery and Translational Research Program

Pan-Mass Challenge Team FLAMES funding

Conquer Cancer Foundation/Sontag Foundation

Publisher

American Society for Clinical Investigation

Subject

General Medicine

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