Purification, Characterization, and Kinetics of Porcine Recombinant Dihydropyrimidine Dehydrogenase

Author:

Rosenbaum Katrin,Schaffrath Barbara,Hagen Wilfred R.,Jahnke Karin,Gonzalez Frank J.,Cook Paul F.,Schnackerz Klaus D.

Publisher

Elsevier BV

Subject

Biotechnology

Reference19 articles.

1. Degradation of pyrimidines and pyrimidine analogs—Pathways and mutual influences;Wasternack;Pharmacol. Ther.,1980

2. Metabolites of 5-fluorouracil in plasma and urine, as monitored by19;Hull;Cancer Res.,1988

3. Experimental neurotoxicity of 5-fluorouracil and its derivatives is due to poisoning by the monofluorinated organic metabolites, monofluoroacetic acid and α-fluoro-β-alanine;Okeda;Acta Neuropathol.,1990

4. Distribution and inhibition of dihydrouracil dehydrogenase activities in human tissues using 5-fluorouracil as a substrate;Ho;Anticancer Res.,1986

5. Purification and properties of dihydrothymine dehydrogenase from rat liver;Shiotani;J. Biol. Chem.,1981

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