Autoantigen-Responsive T Cell Clones Demonstrate Unfocused TCR Cross-Reactivity toward Multiple Related Ligands: Implications for Autoimmunity

Author:

Anderson Ana C.,Waldner Hanspeter,Turchin Vadim,Jabs Claudia,Prabhu Das Mercy,Kuchroo Vijay K.,Nicholson Lindsay B.

Publisher

Elsevier BV

Subject

Immunology

Reference26 articles.

1. MHC-dependent antigen processing and peptide presentation: Providing ligand for T lymphocyte activation;Germain;Cell,1994

2. Altered peptide ligand-induced partial T cell activation: Molecular mechanisms and role in T cell biology;Sloan-Lancaster;Annu. Rev. Immunol.,1996

3. A very high level of crossreactivity is an essential feature of the T-cell receptor;Mason;Immunol. Today,1998

4. Predictable TCR antigen recognition based on peptide scans leads to the identification of agonist ligands with no sequence homology;Hemmer;J. Immunol.,1998

5. Identification of an encephalitogenic determinant of myelin proteolipid protein for SJL mice;Tuohy;J. Immunol.,1989

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