Incomplete systemic lupus erythematosus. Own observation and literature review-Reference-Cited by-同舟云学术

Incomplete systemic lupus erythematosus. Own observation and literature review

Published:2024-01-01 Issue:6 Volume:61 Page:678-688
ISSN:1995-4492
Container-title:Rheumatology Science and Practice
language:
Short-container-title:Naučno-praktičeskaâ revmatologiâ

Author:

Panafidina T. A.¹^ORCID,Popkova T. V.¹^ORCID,Lila A. M.²^ORCID,Nasonov E. L.³^ORCID

Affiliation:

1. V.A. Nasonova Research Institute of Rheumatology

2. V.A. Nasonova Research Institute of Rheumatology; Russian Medical Academy of Continuous Professional Education of the Ministry of Healthcare of the Russian Federation

3. V.A. Nasonova Research Institute of Rheumatology; I.M. Sechenov First Moscow State Medical University of the Ministry of Health Care of Russian Federation (Sechenov University)

Abstract

The term of “incomplete” systemic lupus erythematosus (iSLE) is used when patients have typical clinical and immunological signs of lupus without fulfilling the classification criteria for SLE. Autoantibodies appear in patients years before diagnosis, and the most common clinical manifestations are nonspecific and may be the only symptom of the disease for some time. Progression to definite SLE occurs in 5–57% of patients with iSLE within 1–10 years. There are currently no recommendations for monitoring and treatment of iSLE patients. This article presents the results of our own research and literature analysis on clinical and pathogenetic problems of iSLE.

Publisher

Mediar Press

Subject

Immunology,Immunology and Allergy,Rheumatology

Reference63 articles.

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