RESIST ACINETO test for the rapid detection of NDM and OXA acquired carbapenemases directly from blood culture inAcinetobacterspecies

Abstract

AbstractThe immunochromatographic assay RESIST ACINETO (Coris BioConcept) was evaluated on a collection of 121Acinetobacterspp. clinical isolates, including 104 carbapenemase producers. The strains producing carbapenemases OXA-23, -40, -58, or/and NDM were accurately detected from bacterial cultures and directly from blood cultures, with the exception of an OXA-23/NDM-1-positiveA. radioresistensisolate (only detected through standard culture). The performance of the RESIST ACINETO test was excellent (sensitivity 99%, specificity 100%) on this collection of isolates.