Author:
Wang Yin-Shan,Su Xue-Ting,Ke Li,He Qing-Hua,Chang Da,Nie JingJing,Luo XinLi,Chen Fumei,Xu Jihong,Zhang Cai,Zhang Shudong,Zhang Shuyue,An Huiping,Guo Rui,Yue Suping,Duan Wen,Jia Shichao,Yang Sijia,Yu Yankun,Zhao Yang,Zhou Yang,Chen Li-Zhen,Fan Xue-Ru,Gao Peng,Lv Chenyu,Wu Ziyun,Zhao Yunyan,Quan Xi,Zhao Feng,Mu Yanchao,Yan Yu,Xu Wenchao,Liu Jie,Xing Lixia,Chen Xiaoqin,Wu Xiang,Zhao Lanfeng,Huang Zhijuan,Ren Yanzhou,Hao Hongyan,Li Hui,Wang Jing,Dong Qing,Chen Yanli,Huang Ruiwang,Liu Siman,Wang Yun,Dong Qi,Zuo Xi-Nian
Abstract
ABSTRACTAdverse perinatal factors can disrupt the normal development of the brain, with potential long-term impacts on children’s overall development. Currently, the neuropathological mechanisms by which these factors lead to various neurodevelopmental disorders (NDDs) remain largely unknown. An open resource that integrate perinatal factors with brain and mental health development is essential for investigating NDD-related aetiology. In this Data Descriptor, we introduce a multicentre database containing information on perinatal factors that influence children’s brain-mind development, namely, periCBD, that combines neuroimaging and behavioural phenotypes with perinatal factors associated with a high incidence of NDDs at county/region/central district hospitals. PeriCBD was designed to establish a platform for the investigation of individual differences in brain-mind development among children aged 3–10 years are associated with perinatal factors. Ultimately, our goal was to develop an early prediction and screening model for NDDs that leverages normative data to facilitate NDD aetiology research. Herein, we provide a systematic overview of the data acquisition/cleaning/quality control/sharing, processes of periCBD and present preliminary brain-mind associations.
Publisher
Cold Spring Harbor Laboratory