Author:
Cannavino Jessica,Gupta Rana K.
Abstract
Adipose tissue exhibits a remarkable capacity to expand, contract, and remodel in response to changes in physiological and environmental conditions. Here, we describe recent advances in our understanding of how functionally distinct tissue-resident mesenchymal stromal cell subpopulations orchestrate several aspects of physiological and pathophysiological adipose tissue remodeling, with a particular focus on the adaptations that occur in response to changes in energy surplus and environmental temperature. The study of adipose tissue remodeling provides a vehicle to understand the functional diversity of stromal cells and offers a lens through which several generalizable aspects of tissue reorganization can be readily observed.
Funder
National Institutes of Health
National Institute of Diabetes and Digestive and Kidney Diseases
Publisher
Cold Spring Harbor Laboratory
Subject
Developmental Biology,Genetics
Cited by
1 articles.
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