Emergence and predominance of novel influenza A (H3N2) subclade (3C.2a1b.2a.2a.3a.1) in Kenya and globally in 2023

Author:

Morobe John MwitaORCID,Moraa Edidah,Lambisia Arnold W.ORCID,Mutunga Martin,Kiage Brenda,Katama Esther NyadzuaORCID,Makori TimothyORCID,Nyiro JoyceORCID,Ndwiga LeonardORCID,Nyagwange JamesORCID,Sande CharlesORCID,Ochola-Oyier Lynette IsabellaORCID,Holmes Edward C.,Nokes D. JamesORCID,Githinji GeorgeORCID,Agoti Charles N.ORCID

Abstract

AbstractWe report emergence and predominance of the influenza A (H3N2)subclade 3C.2a1b.2a.2a.3a.1 in Kenya similar to the global clade in 2023. The Kenyan 3C.2a1b.2a.2a.3a.1 viruses have >15 amino acid differences in the HA and NA proteins relative to 2023/24 WHO recommended Northern/Southern Hemisphere influenza vaccine strains.

Publisher

Cold Spring Harbor Laboratory

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