Abstract
AbstractIn developing countries, hepatitis B is spread primarily by the perinatal or horizontal route. Thus, the Senegalese government recommends administering the birth dose of the hepatitis B vaccine (HepB0) within 24 hours of birth. The objective was to identify the determinants of timely administration of HepB0 in Senegal in 2019. A secondary analysis of the demographic and health survey was carried out. The study population consisted of children aged 12 to 23 months. A cluster survey, stratified in urban and rural areas, drawn at two stages, was carried out. Individual interviews were conducted. Logistic regression was applied to estimate the adjusted odds ratio (aOR) and their 95% confidence interval. In total, 1130 children were included. Among them, 48.1% were born to mothers aged 25 to 34, 46.8% were male and 82.6% were born in health facilities. The average time between birth and HepB0 administration was 13.1±46.6 days. Among 747 children vaccinated, only 65.2% were vaccinated within 24 hours of birth. The determinants were maternal age of at least 35 years (aOR= 2.03 [1.29 – 3.20]), primary education of the mother (aOR=1.94 [1.13 – 3. 35]), at least four antenatal care (aOR=1.74 [1.12 – 2.69]), belonging to the central (ORa=0.22 [0.11 – 0.44]) and northern regions (aOR= 0.18 [0.08 – 0.40]), and delivery in a health facility (aOR=3.42 [1.90 – 6.15]). Education and keeping girls in school, local postnatal care in hard-to-reach regions, promotion of antenatal acre and delivery in a health facility should improve the timeliness of HepB0 vaccination.
Publisher
Cold Spring Harbor Laboratory
Reference36 articles.
1. World Health Organization. Global hepatitis report 2017 [Internet]. Geneva: WHO; 2017 [cited 2020 Sep 3]. Available from: https://apps.who.int/iris/bitstream/handle/10665/255016/9789241565455-eng.pdf?sequence=1
2. Eni AO , Soluade MG , Oshamika OO , Efekemo OP , Igwe TT , Onile-Ere OA . Knowledge and Awareness of Hepatitis B Virus Infection in Nigeria. Ann Glob Heal. 2019 Apr;85(1).
3. The prevalence of HBsAg, knowledge and practice of hepatitis B prevention among pregnant women in the Limbe and Muyuka Health Districts of the South West region of Cameroon: a three-year retrospective study;Pan Afr Med J,2019
4. Maternal knowledge and infant uptake of valid hepatitis B vaccine birth dose at routine immunization clinics in Enugu State - Nigeria;Vaccinated,2020