Methylated Cysteine Dioxygenase-1 Gene Promoter in the Serum Is a Potential Biomarker for Hepatitis B Virus-Related Hepatocellular Carcinoma

Author:

Yang Yang12,Fan Yu-Chen12,Gao Shuai1,Dou Cheng-Yun1,Zhang Jian-Jun1,Sun Feng-Kai1,Wang Kai12

Affiliation:

1. Department of Hepatology, Qilu Hospital of Shandong University

2. Institute of Hepatology, Shandong University

Publisher

Tohoku University Medical Press

Subject

General Biochemistry, Genetics and Molecular Biology,General Medicine

Reference32 articles.

1. Andresen, K., Boberg, K.M., Vedeld, H.M., Honne, H., Hektoen, M., Wadsworth, C.A., Clausen, O.P., Karlsen, T.H., Foss, A., Mathisen, O., Schrumpf, E., Lothe, R.A. & Lind, G.E. (2012) Novel target genes and a valid biomarker panel identified for cholangiocarcinoma. Epigenetics, 7, 1249-1257.

2. Bossuyt, P.M., Reitsma, J.B., Bruns, D.E., Gatsonis, C.A., Glasziou, P.P., Irwig, L.M., Lijmer, J.G., Moher, D., Rennie, D. & de Vet, H.C.; Standards for Reporting of Diagnostic, Accuracy (2003) Towards complete and accurate reporting of studies of diagnostic accuracy: the STARD initiative. Standards for Reporting of Diagnostic Accuracy. Clin. Chem., 49, 1-6.

3. Brait, M., Ling, S., Nagpal, J.K., Chang, X., Park, H.L., Lee, J., Okamura, J., Yamashita, K., Sidransky, D. & Kim, M.S. (2012) Cysteine dioxygenase 1 is a tumor suppressor gene silenced by promoter methylation in multiple human cancers. PLoS One, 7, e44951.

4. Bruix, J., Boix, L., Sala, M. & Llovet, J.M. (2004) Focus on hepatocellular carcinoma. Cancer Cell, 5, 215-219.

5. Bruix, J., Sherman, M., Llovet, J.M., Beaugrand, M., Lencioni, R., Burroughs, A.K., Christensen, E., Pagliaro, L., Colombo, M. & Rodes, J.; EASL Panel of Experts on HCC (2001) Clinical management of hepatocellular carcinoma. Conclusions of the Barcelona-2000 EASL conference. European Association for the Study of the Liver. J. Hepatol., 35, 421-430.

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