The proportion of tumor-stroma as a strong prognosticator for stage II and III colon cancer patients: validation in the VICTOR trial

Author:

Huijbers A.,Tollenaar R.A.E.M.,v Pelt G.W.,Zeestraten E.C.M.,Dutton S.,McConkey C.C.,Domingo E.,Smit V.T.H.B.M.,Midgley R.,Warren B.F.,Johnstone E.C.,Kerr D.J.,Mesker W.E.

Funder

Rotary Lisse-Bollenstreek

Sascha Swarttouw foundation

Merck

Publisher

Elsevier BV

Subject

Oncology,Hematology

Reference21 articles.

1. Adjuvant chemotherapy versus observation in patients with colorectal cancer: a randomised study;Gray;Lancet,2007

2. Comparison of fluorouracil with additional levamisole, higher-dose folinic acid, or both, as adjuvant chemotherapy for colorectal cancer: a randomised trial;QUASAR Collaborative Group;Lancet,2000

3. Presence of a high amount of stroma and downregulation of SMAD4 predict for worse survival for stage I-II colon cancer patients;Mesker;Cell Oncol,2009

4. The carcinoma-stromal ratio of colon carcinoma is an independent factor for survival compared to lymph node status and tumor stage;Mesker;Cell Oncol,2007

5. The proportion of tumour cells is an independent predictor for survival in colorectal cancer patients;West;Br J Cancer,2010

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