Bone marrow-derived CXCR4-overexpressing MSCs display increased homing to intestine and ameliorate colitis-associated tumorigenesis in mice

Author:

Zheng Xiao-Bin12,He Xiao-Wen12,Zhang Long-Juan3,Qin Hua-Bo12,Lin Xu-Tao124,Liu Xuan-Hui12,Zhou Chi12,Liu Hua-Shan12,Hu Tuo12,Cheng Hai-Chun5,He Xiao-Sheng12,Wu Xian-Rui12,Chen Yu-Feng12,Ke Jia12,Wu Xiao-Jian12,Lan Ping12

Affiliation:

1. Department of Colorectal Surgery, The Sixth Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, P.R. China

2. Guangdong Provincial Key Laboratory of Colorectal and Pelvic Floor Diseases, The Sixth Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, P.R. China

3. Laboratory of Surgery, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, P.R. China

4. Department of Gastrointestinal Endoscopy, The Sixth Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, P.R. China

5. Department of Gastrointestinal Surgery, Shenzhen Baoan Shajing People’s Hospital, Guangzhou Medical University, Shenzhen, Guangdong, P.R. China

Funder

National Key Clinical Discipline

National Natural Science Foundation of China

Guangdong Natural Science Foundation

Science and Technology Planning Project of Guangdong Province

Publisher

Oxford University Press (OUP)

Subject

Gastroenterology

Reference70 articles.

1. Crohn’s disease;Torres;Lancet,2017

2. Ulcerative colitis;Ungaro;Lancet,2017

3. The continuing uncertainty about cancer risk in inflammatory bowel disease;Adami;Gut,2016

4. Review article: the incidence and prevalence of colorectal cancer in inflammatory bowel disease;Munkholm;Aliment Pharmacol Ther,2003

5. Recurrence and survival rates of inflammatory bowel disease-associated colorectal cancer following postoperative chemotherapy: a comparative study;Dugum;Gastroenterol Rep,2017

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