1. Center for Precision Medicine Research, Marshfield Clinic Research Institute , Marshfield, WI 54449 , USA
2. Department of Internal Medicine-Pediatrics, Marshfield Clinic Health System , Marshfield, WI 54449 , USA
3. Hinda and Arthur Marcus Institute for Aging Research at Hebrew Senior Life , Boston, MA , USA
4. Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School , Boston, MA , USA
5. Department of Surgical Oncology, Marshfield Clinic Health System , Marshfield, WI 54449 , USA
6. Institute of Bioinformatics and Systems Biology, National Yang Ming Chiao Tung University , Hsinchu , Taiwan
7. College of Health Sciences, Kaohsiung Medical University , Kaohsiung , Taiwan
8. Biomedical Engineering, National Yang Ming Chiao Tung University , Hsinchu , Taiwan