Contemporary Management of Staphylococcus aureus Bacteremia—Controversies in Clinical Practice

Author:

Minter Daniel J1ORCID,Appa Ayesha12ORCID,Chambers Henry F12,Doernberg Sarah B1

Affiliation:

1. Division of Infectious Diseases, Department of Medicine, University of California, San Francisco , San Francisco, California , USA

2. Division of HIV, Infectious Diseases, and Global Medicine at Zuckerberg San Francisco General Hospital, Department of Medicine, University of California, San Francisco , San Francisco, California , USA

Abstract

Abstract Staphylococcus aureus bacteremia (SAB) carries a high risk for excess morbidity and mortality. Despite its prevalence, significant practice variation continues to permeate clinical management of this syndrome. Since the publication of the 2011 Infectious Diseases Society of America (IDSA) guidelines on management of methicillin-resistant Staphylococcus aureus infections, the field of SAB has evolved with the emergence of newer diagnostic strategies and therapeutic options. In this review, we seek to provide a comprehensive overview of the evaluation and management of SAB, with special focus on areas where the highest level of evidence is lacking to inform best practices.

Publisher

Oxford University Press (OUP)

Subject

Infectious Diseases,Microbiology (medical)

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