Face off: a metabolic enzyme becomes a protein phosphatase
Author:
Affiliation:
1. Department of Oncology, Qingdao Cancer Institute, The Affiliated Hospital of Qingdao University, Qingdao University , Qingdao 266071 , China
2. Ben May Department for Cancer Research, The University of Chicago , Chicago, IL 60637 , USA
Funder
National Natural Science Foundation of China
Natural Science Foundation of Shandong Province
University of Chicago
Publisher
Oxford University Press (OUP)
Subject
Cell Biology,Drug Discovery,Biochemistry,Biotechnology
Link
https://academic.oup.com/proteincell/advance-article-pdf/doi/10.1093/procel/pwad006/49385052/pwad006.pdf
Reference18 articles.
1. Canonical and non-canonical roles of PFKFB3 in brain tumors;Alvarez;Cells,2021
2. Metabolic enzyme PFKFB4 activates transcriptional coactivator SRC-3 to drive breast cancer;Dasgupta;Nature,2018
3. Revisited metabolic control and reprogramming cancers by means of the Warburg Effect in tumor cells;Fukushi;Int J Mol Sci,2022
4. Metabolic phosphatase moonlights for proteins;Gerber;Nat Cell Biol,2022
5. Aerobic glycolysis promotes tumor immune evasion by hexokinase2-mediated phosphorylation of IkappaBalpha;Guo;Cell Metab,2022
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