Kimura’s disease: a rare cause of chronic neck lymphadenopathy

Author:

Kok Kenneth Y Y1,Lim Edwin C C2

Affiliation:

1. Discipline of Medicine, Pengiran Anak Puteri Rashidah Sa’adatul Bolkiah Institute of Health Sciences, Universiti Brunei Darussalam, Jalan Tungku-Link, Brunei Darussalam

2. Department of Pathology, Raja Isteri Pengiran Anak Saleha Hospital, Bandar Seri Begawan, Brunei Darussalam

Abstract

Abstract Kimura’s disease is a rare chronic inflammatory disorder of unknown etiology which typically presents with subcutaneous nodules in the head and neck region and is frequently associated with regional lymphadenopathy or salivary gland enlargement. Peripheral blood eosinophilia and elevated serum immunoglobulin E levels are constant features of the disease. We present herein a 31-year-old male patient who presented with chronic neck lymphadenopathy. Kimura’s disease was diagnosed on fine needle aspiration cytology, the patient initially decided not to have further intervention. He presented 6 years later with lymphadenopathy and was treated with surgery. The diagnosis of Kimura’s disease was confirmed on histopathology. This patient had the disease for 6 years and did not have the typical features of peripheral eosinophilia and raise serum IgE level.

Publisher

Oxford University Press (OUP)

Subject

Surgery

Reference15 articles.

1. Eosinophilic hyperplastic lymphogranuloma. Comparison with Mikulicz’s disease;Kim;Chin Med J (Engl),1937

2. On the unusual granulation combined with hyperplastic changes of lymphatic tissue;Kimura;Trans Soc Pathol Jpn,1948

3. Human polyomavirus-6 infecting lymph nodes of a patient with an angiolymphoid hyperplasia with eosinophilia or Kimura disease;Rascovan;Clin Infect Dis,2016

4. Kimura disease: a rare case report;Abhange;Ann Pathol Lab Med,2018

5. Kimura’s disease: a diagnostic challenge;Shetty;Pediatrics,2002

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