Necrotising fasciitis, invasive Group A Streptococcus (iGAS) infection; a case series of 8 patients requiring surgical debridement in one trauma unit within 9 months

Author:

Salim Omar-Adam1ORCID,Hillier-Smith Ryan2,Ardolino Antonella2

Affiliation:

1. Trauma and Orthopaedics, Basingstoke and North Hampshire NHS Foundation Trust , Hampshire RG24 9NA , United Kingdom

2. Hampshire Hospitals NHS Foundation Trust , Hampshire RG24 9NA , United Kingdom

Abstract

Abstract Necrotising fasciitis (NF) is a rare but life-threatening skin and soft tissue infection. It requires urgent surgical debridement. The most common cause of monomicrobial NF is invasive Group A Streptococcus (IGAS). We present eight patients who were all treated in a single trauma unit within a 9-month period. All cases required surgical debridement and had positive microbiology testing for IGAS. The eight patients did not present typically for NF, nor did they all have typical risk factors for the development of NF. The in-hospital mortality rate was 37.5%. This series represents an epidemiological spike of IGAS infections causing NF. The findings from this series could inform future practice if similar spikes were to be encountered.

Publisher

Oxford University Press (OUP)

Reference15 articles.

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2. Necrotising fasciitis in the North-East of Scotland: a 10-year retrospective review;Neilly;Ann R Coll Surg Engl,2019

3. Patient’s characteristics and outcomes in necrotising soft-tissue infections: results from a Scandinavian, multicentre, prospective cohort study;Madsen;Intensive Care Med,2019

4. Invasive Group A Streptococcal infection. An update on the epidemiology and orthopaedic management;Brown,2010

5. Necrotizing fasciitis;Bellapianta;J Am Acad Orthop Surg,2009

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