Protamine-derived peptide RPR (Arg-Pro-Arg) ameliorates oleic acid-induced lipogenesis via the PepT1 pathway in HepG2 cells
Author:
Affiliation:
1. Department of Applied Life Science, Faculty of Applied Biological Sciences, Gifu University , Gifu , Japan
2. Fordays Co., Ltd., Fordays Nutritional Research Center , 2-24-16 Nakacho, Koganei City, Tokyo , Japan
Abstract
Funder
Ministry of Education, Culture, Sports, Science and Technology
Fordays Co., Ltd.
Publisher
Oxford University Press (OUP)
Subject
Organic Chemistry,Molecular Biology,Applied Microbiology and Biotechnology,General Medicine,Biochemistry,Analytical Chemistry,Biotechnology
Link
https://academic.oup.com/bbb/advance-article-pdf/doi/10.1093/bbb/zbac197/48497570/zbac197.pdf
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3. Identification of a novel cholesterol-lowering dipeptide, phenylalanine-proline (FP), and its down-regulation of intestinal ABCA1 in hypercholesterolemic rats and Caco-2 cells;Banno;Sci Rep,2019
4. Cloning and characterization of the human stearoyl-CoA desaturase gene promoter: Transcriptional activation by sterol regulatory element binding protein and repression by polyunsaturated fatty acids and cholesterol;Bené;Biochem Biophys Res Commun,2001
5. Peptides released from bovine α-lactalbumin by simulated digestion alleviated free fatty acids-induced lipid accumulation in HepG2 cells;Chen;J Funct Foods,2021
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