Socioeconomic differences in outcomes after hospital admission for atrial fibrillation or flutter

Author:

Hagengaard Louise12,Andersen Mikkel Porsborg23,Polcwiartek Christoffer1245ORCID,Larsen Jacob Mosgaard1,Larsen Mogens Lytken14,Skals Regitze Kuhr2,Hansen Steen Møller24,Riahi Sam14,Gislason Gunnar6ORCID,Torp-Pedersen Christian1234,Søgaard Peter14,Kragholm Kristian Hay27

Affiliation:

1. Department of Cardiology, Aalborg University Hospital, Hobrovej 18-22, 9000 Aalborg, Denmark

2. Unit of Epidemiology and Biostatistics, Aalborg University Hospital, Søndre Skovvej 15, 9000 Aalborg, Denmark

3. Department of Clinical Research, Nordsjællands Hospital, Dyrehvaevej 29, 3400 Hillerød, Denmark

4. Department of Clinical Medicine, Aalborg University, Søndre Skovvej 15, 9000 Aalborg, Denmark

5. Division of Cardiology, Duke University Medical Center, Erwin Road, Durham, NC 27710, USA

6. Department of Cardiology, Copenhagen University Hospital Gentofte, Gentofte Hospitalsvej 1, 2900 Hellerup, Denmark

7. Department of Cardiology, Hjørring Regional Hospital, Bispensgade 37, 9800 Hjørring, Denmark

Abstract

Abstract Aims To examine socioeconomic differences in care and outcomes in a 1-year period beginning 30 days after hospital discharge for first-time atrial fibrillation or flutter (AF) hospitalization. Methods and results This nationwide register-based follow-up cohort study investigated AF 30-day discharge survivors in Denmark during 2005–2014 and examined associations between patient’s socioeconomic status (SES) and selected outcomes during a 1-year follow-up period beginning 30 days post-discharge after first-time hospitalization for AF. Patient SES was defined in four groups (lowest, second lowest, second highest, and highest) according to each patient’s equivalized income. SES of the included 150 544 patients was: 27.7% lowest (n = 41 648), 28.1% second lowest (n = 42 321), 23.7% second highest (n = 35 656), and 20.5% highest (n = 30 919). Patients of lowest SES were older and more often women. Within 1-year follow-up, patients of lowest SES were less often rehospitalized or seen in outpatient clinics due to AF, or treated with cardioversion or ablation and were slightly more often diagnosed with stroke and heart failure (HF) and significantly more likely to die (16.1% vs. 14.9%, 11.3% and 8.1%). Hazard ratios for all-cause mortality were 0.64 (95% confidence interval 0.61–0.68) for highest vs. lowest SES, adjusted for CHA2DS2-VASc score, chronic obstructive pulmonary disease, rate- and rhythm-controlling drugs, and cohabitation status. Conclusion In 30-day survivors of first-time hospitalization due to AF, lowest SES is associated with increased 1-year all-cause and cardiovascular mortality and fewer cardioversions, ablations, readmissions, and outpatient contacts due to AF. Our findings indicate a need for socially differentiated rehabilitation following hospital discharge for first-time AF.

Funder

Danish Heart Foundation

Eva and Henry Frænkel Memorial Foundation

Bayer, Bristol Myers Squibb, Pfizer

Boehringer Ingelheim

GE Healthcare

BIOTRONIK

Astra Zeneca

Novartis

The Laerdal Foundation

Publisher

Oxford University Press (OUP)

Subject

Cardiology and Cardiovascular Medicine,Health Policy

Reference20 articles.

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3. Cardiac rehabilitation: health characteristics and socio-economic status among those who do not attend;Nielsen;Eur J Public Health,2008

4. Socially differentiated cardiac rehabilitation: can we improve referral, attendance and adherence among patients with first myocardial infarction?;Meillier;Scand J Soc Med,2012

5. Medication prescription and adherence disparities in non valvular atrial fibrillation patients: an Italian portrait from the ARAPACIS study;Raparelli;Intern Emerg Med,2014

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