Multimodality imaging in patients with heart failure and preserved ejection fraction: an expert consensus document of the European Association of Cardiovascular Imaging

Author:

Smiseth Otto A123,Morris Daniel A4,Cardim Nuno5,Cikes Maja6,Delgado Victoria7,Donal Erwan89,Flachskampf Frank A10,Galderisi Maurizio11,Gerber Bernhard L12,Gimelli Alessia13,Klein Allan L14,Knuuti Juhani15,Lancellotti Patrizio1617,Mascherbauer Julia18,Milicic Davor6,Seferovic Petar1920,Solomon Scott21,Edvardsen Thor123,Popescu Bogdan A22,Bertrand Philippe B,Dweck Marc,Haugaa Kristina H,Sade Leyla Elif,Stankovic Ivan,Ha Jong-Won,Nagueh Sherif,Oh Jae K,Ohte Nobuyuki,Cosyns Bernard,

Affiliation:

1. Department of Cardiology, Oslo University Hospital, Rikshospitalet, Sognsvannsveien 20, Oslo, Norway

2. Institute for Surgical Research, Oslo University Hospital, Rikshospitalet, Sognsvannsveien 20, Oslo, Norway

3. Institute of Clinical Medicine, University of Oslo, Oslo, Norway

4. Department of Internal Medicine and Cardiology, Campus Virchow Klinikum, Charité Universitätsmedizin Berlin, Berlin, Germany

5. Cardiology Department, Hospital da Luz, Av. Lusíada, N° 100, Lisbon, Portugal

6. Department of Cardiovascular Diseases, University of Zagreb School of Medicine and University Hospital Center Zagreb, Zagreb, Croatia

7. Department of Cardiology, Leiden University Medical Centre, Albinusdreef 2, Leiden 2300 RC, The Netherlands

8. Service de Cardiologie Et Maladies Vasculaires Et CIC-IT 1414, CHU Rennes, 35000 Rennes, France

9. Université de Rennes 1, LTSI, 35000 Rennes, France

10. Department of Medical Sciences, Clinical Physiology and Cardiology, Uppsala University Hospital, Uppsala, Sweden

11. Department of Advanced Biomedical Sciences, Federico II University, Naples, Italy

12. Division of Cardiology, Department of Cardiovascular Diseases, Cliniques Universitaires St. Luc, Pôle de Recherche Cardiovasculaire (CARD), Institut de Recherche Expérimentale et Clinique (IREC), Université Catholique de Louvain, Av Hippocrate, 10/2806 Brussels, Belgium

13. Fondazione Toscana Gabriele Monasterio, Via Moruzzi, 1, Pisa 56124, Italy

14. Section of Cardiovascular Imaging, Heart and Vascular Institute, Cleveland Clinic, Cleveland, OH, USA

15. Turku PET Centre, University of Turku, and Turku University Hospital, Turku, Finland

16. Department of Cardiology, University of Liège Hospital, Domaine Universitaire du Sart Tilman, Liège B4000, Belgium

17. Gruppo Villa Maria Care and Research, Maria Cecilia Hospital, Cotignola, and Anthea Hospital, Bari, Italy

18. Department of Internal Medicine 3, Karl Landsteiner University of Health Sciences, University Hospital St. Pölten, Krems, Austria

19. Department of Cardiology, Clinical Center of Serbia, Belgrade, Serbia

20. Faculty of Medicine, University of Belgrade, Belgrade, Serbia

21. Division of Cardiovascular Medicine, Brigham and Women's Hospital, Boston, MA, USA

22. Department of Cardiology, University of Medicine and Pharmacy “Carol Davila”, Euroecolab, Emergency Institute for Cardiovascular Diseases “Prof. Dr. C. C. Iliescu”, Sos. Fundeni 258, sector 2, 022328 Bucharest, Romania

Abstract

Abstract Nearly half of all patients with heart failure (HF) have a normal left ventricular (LV) ejection fraction (EF) and the condition is termed heart failure with preserved ejection fraction (HFpEF). It is assumed that in these patients HF is due primarily to LV diastolic dysfunction. The prognosis in HFpEF is almost as severe as in HF with reduced EF (HFrEF). In contrast to HFrEF where drugs and devices are proven to reduce mortality, in HFpEF there has been limited therapy available with documented effects on prognosis. This may reflect that HFpEF encompasses a wide range of different pathological processes, which multimodality imaging is well placed to differentiate. Progress in developing therapies for HFpEF has been hampered by a lack of uniform diagnostic criteria. The present expert consensus document from the European Association of Cardiovascular Imaging (EACVI) provides recommendations regarding how to determine elevated LV filling pressure in the setting of suspected HFpEF and how to use multimodality imaging to determine specific aetiologies in patients with HFpEF.

Publisher

Oxford University Press (OUP)

Subject

Cardiology and Cardiovascular Medicine,Radiology, Nuclear Medicine and imaging,General Medicine

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