Phase 3 study of ceritinib vs chemotherapy in ALK-rearranged NSCLC patients previously treated with chemotherapy and crizotinib (ASCEND-5): Japanese subset

Author:

Kiura Katsuyuki1,Imamura Fumio2,Kagamu Hiroshi3,Matsumoto Shingo4,Hida Toyoaki5,Nakagawa Kazuhiko6,Satouchi Miyako7,Okamoto Isamu8,Takenoyama Mitsuhiro9,Fujisaka Yasuhito10,Kurata Takayasu11,Ito Masayuki12,Tokushige Kota12,Hatano Ben12,Nishio Makoto13

Affiliation:

1. Okayama University Hospital, Okayama

2. Osaka International Cancer Institute, Osaka

3. Niigata University Medical and Dental Hospital, Niigata

4. National Cancer Center Hospital East, Kashiwa

5. Aichi Cancer Center, Nagoya

6. Kindai University Hospital, Osaka

7. Hyogo Cancer Center, Akashi

8. Research Institute for Diseases of the Chest, Graduate School of Medical Sciences, Kyushu University, Fukuoka

9. Kyusyu Cancer Center, Fukuoka

10. Osaka Medical College Hospital, Osaka

11. Kansai Medical University Hospital, Osaka

12. Novartis Pharma K.K., Tokyo

13. The Cancer Institute Hospital of JFCR, Tokyo, Japan

Publisher

Oxford University Press (OUP)

Subject

Cancer Research,Radiology, Nuclear Medicine and imaging,Oncology,General Medicine

Reference19 articles.

1. Identification of the transforming EML4-ALK fusion gene in non-small-cell lung cancer;Soda;Nature,2007

2. Clinical features and outcome of patients with non-small-cell lung cancer who harbor EML4-ALK;Shaw;J Clin Oncol,2009

3. First-Line Crizotinib versus chemotherapy in ALK-positive lung cancer;Solomon;New Engl J Med,2014

4. Crizotinib versus chemotherapy in advanced ALK-positive lung cancer;Shaw;New Engl J Med,2013

5. Mechanisms of acquired crizotinib resistance in ALK-rearranged lung cancers;Katayama;Sci Transl Med,2012

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