Retrospective analysis of fungemia among children in Anka General Hospital, Nigeria, from October 2018 to November 2021: a case series-Reference-Cited by-同舟云学术

Retrospective analysis of fungemia among children in Anka General Hospital, Nigeria, from October 2018 to November 2021: a case series

Published:2023-07-01 Issue:7 Volume:2023 Page:
ISSN:2053-8855
Container-title:Oxford Medical Case Reports
language:en
Short-container-title:

Author:

Olubiyo Ruth¹^ORCID,Chukwumeze Frederick²,Lawal Abdulhakeem Mohammed²,Oloruntuyi Gbemisola²,Musoka Honore²,Augustine Nwogu Ahamba³,Abdullahi Ibrahim⁴,Shehu Ismail⁴,Egwuenu Abiodun⁵,Clezy Kate⁶,Oluyide Bukola⁷,Gomez Diana⁶,Sherlock Mark⁶,Lenglet Annick⁸⁹,Repetto Ernestina¹⁰

Affiliation:

1. Médecins Sans Frontières Medical Department, , Sokoto, Sokoto, Nigeria

2. Médecins Sans Frontières Medical Department, , Anka, Zamfara, Nigeria

3. Anka General Hospital Medical Department, , Anka, Zamfara, Nigeria

4. Noma Children Hospital Microbiology Unit, , Sokoto, Sokoto, Nigeria

5. Nigerian Center for Disease Control (NCDC) , FCT Abuja, Nigeria

6. Médecins Sans Frontières, Operational Centre Amsterdam Public Health Department, , The Netherlands

7. Médecins Sans Frontières Medical Department, , Abuja, Nigeria

8. International Centre for Antimicrobial Resistance Solutions (ICARS) , Copenhagen, Denmark

9. University of KwaZulu-Natal Antimicrobial Research Unit, School of Health Sciences, , Durban, South Africa

10. Médecins Sans Frontieres, Operational Center Geneva Antimicrobial Resistance Unit, , Geneva, Switzerland

Abstract

Abstract Yeast-related bloodstream infections (BSIs) in pediatric patients are associated with severe acute malnutrition (SAM), hematological/oncological malignancies and admission to an intensive care unit. These infections are rarely described from low- and middle-income countries. We describe a case series of pediatric patients diagnosed with severe sepsis and yeast isolated from their blood culture in a conflict-affected area of Nigeria from October 2018 to November 2021. We identified 20 patients with yeast BSIs, among whom 17 were also diagnosed with SAM. We recommend the inclusion of antifungal treatment for empiric treatment guidelines for children with SAM and severe sepsis in similar settings.

Publisher

Oxford University Press (OUP)

Subject

Infectious Diseases,Microbiology,Parasitology

Link

https://academic.oup.com/omcr/article-pdf/2023/7/omad071/50901450/omad071.pdf

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