CD8+ T-cell exhaustion in cancer: mechanisms and new area for cancer immunotherapy
Author:
Affiliation:
1. Nanjing Medical University
2. Xuzhou Medical University
3. Department of Clinical Pharmacology, Hospital of PLA
4. Department of Integrated Traditional Chinese Medicine and Western Medicine, Beijing Youan Hospital, Capital Medical University
Funder
Jiangsu Province
Publisher
Oxford University Press (OUP)
Link
http://academic.oup.com/bfg/article-pdf/18/2/99/28210825/ely006.pdf
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3. Induction and exhaustion of lymphocytic choriomeningitis virus-specific cytotoxic T lymphocytes visualized using soluble tetrameric major histocompatibility complex class I-peptide complexes;Gallimore;J Exp Med,1998
4. A significant number of human immunodeficiency virus epitope-specific cytotoxic T lymphocytes detected by tetramer binding do not produce gamma interferon;Goepfert;J Virol,2000
5. High viral burden in the presence of major HIV-specific CD8(+) T cell expansions: evidence for impaired CTL effector function;Kostense;Eur J Immunol,2001
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