THE INFLUENCE OF LOW-DOSE OCCUPATIONAL RADIATION EXPOSURE ON PERIPHERAL BLOOD CELLS IN A COHORT OF CHINESE MEDICAL RADIATION WORKERS

Author:

Wang Gui1,Xu Chang2ORCID,Li Shixia1,Zhang Daguang2,Chen Yue3,Liu Juntian1,Liu Ningbo2

Affiliation:

1. Department of Disease Prevention, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin, Tianjin’ s Clinical Research Center for Cancer, Tianjin, China

2. Department of Radiotherapy, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin, Tianjin’ s Clinical Research Center for Cancer, Tianjin, China

3. Department of Medical Service, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin, Tianjin’ s Clinical Research Center for Cancer, Tianjin, China

Abstract

Abstract Objectives The study aims to assess the change of peripheral blood cell numbers following protracted low-dose radiation exposure among medical radiation workers. Methods A cohort of 375 Chinese medical workers were followed for 5 years (2015–19) and recorded the changes in blood cells and cumulative doses. T-test, least significant difference-T test, variance analysis and correlation analysis were utilized in this study. Results Compared with the control group, the white blood cells, hemoglobin counts and the ratio of eosinophils in the study group showed a downward trend. The differences in blood cells between groups were mainly found in the number of red blood cells. In a short cumulative time, such as 1 or 3 years, a correlation between the cumulative dose and the quantity of blood cells was detected, but not at 5 years. Conclusions There is no significant difference in the blood cell counts between different types of work, and the long-term cumulative dose has not been statistically correlated with the number of blood cells. So that the number of peripheral blood cells can no longer be used as a good indicator of radiation damage.

Publisher

Oxford University Press (OUP)

Subject

Public Health, Environmental and Occupational Health,Radiology, Nuclear Medicine and imaging,General Medicine,Radiation,Radiological and Ultrasound Technology

Reference17 articles.

1. Sex difference of radiation response in occupational and accidental exposure;Narendran;Front. Genet.,2019

2. Protracted low-dose radiation exposure and cataract in a cohort of Chinese industry radiographers;Lian;Occup. Environ. Med.,2015

3. Radiation and checkpoint blockade immunotherapy: radiosensitisation and potential mechanisms of synergy;Sharabi;Lancet Oncol.,2015

4. Immunomodulatory effects of stereotactic body radiation therapy: preclinical insights and clinical opportunities;Marciscano;Int. J. Radiat. Oncol. Biol. Phys.,2019

5. Survival in patients with severe lymphopenia following treatment with radiation and chemotherapy for newly diagnosed solid tumors;Grossman;J. Natl. Compr. Cancer Netw.,2015

Cited by 1 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

全球学者库

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"全球学者库"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前全球学者库共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2023 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3