Artificial intelligence in cardiovascular medicine: clinical applications

Author:

Lüscher Thomas F1234ORCID,Wenzl Florian A4567ORCID,D’Ascenzo Fabrizio8ORCID,Friedman Paul A9ORCID,Antoniades Charalambos10ORCID

Affiliation:

1. Royal Brompton and Harefield Hospitals , London , UK

2. National Heart and Lung Institute, Imperial College London , UK

3. Cardiovascular Academic Group, King’s College , London , UK

4. Center for Molecular Cardiology, University of Zurich , Wagistrasse 12, 8952 Schlieren – Zurich , Switzerland

5. National Disease Registration and Analysis Service, NHS , London , UK

6. Department of Cardiovascular Sciences, University of Leicester , Leicester , UK

7. Department of Clinical Sciences, Karolinska Institutet , Stockholm , Sweden

8. Division of Cardiology, Cardiovascular and Thoracic Department, Città della Salute e della Scienza Hospital , Turin , Italy

9. Department of Cardiovascular Medicine, Mayo Clinic and Mayo Foundation , Rochester, MN , USA

10. Acute Multidisciplinary Imaging and Interventional Centre, RDM Division of Cardiovascular Medicine, University of Oxford , Headley Way, Headington, Oxford OX39DU , UK

Abstract

Abstract Clinical medicine requires the integration of various forms of patient data including demographics, symptom characteristics, electrocardiogram findings, laboratory values, biomarker levels, and imaging studies. Decision-making on the optimal management should be based on a high probability that the envisaged treatment is appropriate, provides benefit, and bears no or little potential harm. To that end, personalized risk–benefit considerations should guide the management of individual patients to achieve optimal results. These basic clinical tasks have become more and more challenging with the massively growing data now available; artificial intelligence and machine learning (AI/ML) can provide assistance for clinicians by obtaining and comprehensively preparing the history of patients, analysing face and voice and other clinical features, by integrating laboratory results, biomarkers, and imaging. Furthermore, AI/ML can provide a comprehensive risk assessment as a basis of optimal acute and chronic care. The clinical usefulness of AI/ML algorithms should be carefully assessed, validated with confirmation datasets before clinical use, and repeatedly re-evaluated as patient phenotypes change. This review provides an overview of the current data revolution that has changed and will continue to change the face of clinical medicine radically, if properly used, to the benefit of physicians and patients alike.

Publisher

Oxford University Press (OUP)

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